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Proud moment: Pierce with (L-R) Charlotte, Christopher, his father Bill, Charlotte's daughter Isabella, his mother May and son Sean collecting his honorary OBE in July 2003 Family ties: Charlotte and her brother Chris in September 2003In an interview with the Mail on Sunday in March, Mr Brosnan spoke about drawing on his own family's experiences in order to play a widower who falls in love with a cancer sufferer in his latest film Love Is All You Need.

Such things draw a mark across your heart and it’s always a part of your life.

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The star went public with her decision in May, saying that she wanted to encourage women to get tested for the defective gene so that they could take preventive action if necessary.

Many celebrities took to Twitter to offer their condolences.

Former Bond girl Denise Richards, who starred alongside Mr Brosnan in The World is Not Enough, wrote on Twitter: 'My heart goes out to Pierce Brosnan & his family...

Charlotte, who was adopted by the actor after he married her mother, leaves behind her husband, artist Alex Smith, and children Isabella, 15, and eight-year-old Lucas.

She is also survived by her brothers Christopher, Sean, Dylan and Paris.

Last modified 05-Sep-2016 21:30